Type 5 Cyclic Nucleotide Phosphodiesterases

A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an important role in regulating VASCULAR SMOOTH MUSCLE contraction.

Also Known As:

Cyclic Nucleotide Phosphodiesterases, Type 5; PDE5 Phosphodiesterases; Phosphodiesterase 5; Phosphodiesterase 5A; Phosphodiesterase 5A, cGMP-Specific; Phosphodiesterase Type 5; Phosphodiesterase Type V; Phosphodiesterase V; Phosphodiesterase-5; cGMP-Binding, cGMP-Specific 3',5'-cyclic Nucleotide Phosphodiesterase; Phosphodiesterase 5A, cGMP Specific; Phosphodiesterases, PDE5; Type 5, Phosphodiesterase; Type V, Phosphodiesterase; cGMP-Specific Phosphodiesterase 5A

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Esterases: 1594
      - Phosphoric Diester Hydrolases: 2427
        3',5'-Cyclic-AMP Phosphodiesterases: 189
        Type 5 Cyclic Nucleotide Phosphodiesterases: 1574
        3',5'-Cyclic-GMP Phosphodiesterases
        Type 5 Cyclic Nucleotide Phosphodiesterases: 1574
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intracellular Signaling Peptides and Proteins: 32
    - 3',5'-Cyclic-AMP Phosphodiesterases: 189
      - Type 5 Cyclic Nucleotide Phosphodiesterases: 1574
    - 3',5'-Cyclic-GMP Phosphodiesterases
      - Type 5 Cyclic Nucleotide Phosphodiesterases: 1574

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Ja Jong Kim Research Topics

Disease

Drug/Important Bio-Agent (IBA)